Incretin analogues
Incretin Analogues for Research: Retatrutide, Tirzepatide, Semaglutide
GLP-1, GIP, glucagon and amylin receptor agonists for metabolic research.
Incretin analogues in research
Incretins are gut hormones that signal to the pancreas and the brain after a meal, shaping how the body handles glucose. GLP-1 and GIP are the best described. Incretin analogues are peptides designed to mimic or strengthen these signals, and laboratories study them in vitro and in animal models. MOLEVIA offers twelve products in this category, from single agonists to blends in one vial.
Receptors the analogues act on
Mono, dual and triple agonists
- GLP-1 agonists: semaglutide, liraglutide and dulaglutide. The GLP-1 receptor takes part in insulin secretion signalling and glucose homeostasis.
- Dual agonists: tirzepatide (GIP and GLP-1), mazdutide (GLP-1 and glucagon) and survodutide (glucagon and GLP-1).
- Triple agonist: retatrutide, which acts on GIP, GLP-1 and glucagon receptors.
- Amylin analogues: cagrilintide (amylin and calcitonin receptors) and eloralintide, which is selective for the amylin receptor.
What the status means
The status column shows whether a substance is registered in approved medicines or studied in clinical trials, based on published literature.
Comparison table
| Substance | Receptors | Status | Sizes in the catalogue |
|---|---|---|---|
| Retatrutide | GIP, GLP-1, glucagon | In clinical trials | 5-100 mg |
| Tirzepatide | GIP, GLP-1 | Registered as a medicine | 5-120 mg |
| Semaglutide | GLP-1 | Registered as a medicine | 2-50 mg |
| Cagrilintide | Amylin, calcitonin | In clinical trials | 2-20 mg |
| Liraglutide | GLP-1 | Registered as a medicine | 5-30 mg |
| Dulaglutide | GLP-1 | Registered as a medicine | 5-10 mg |
| Mazdutide | GLP-1, glucagon | In clinical trials | 5-10 mg |
| Survodutide | Glucagon, GLP-1 | In clinical trials | 10 mg |
| Eloralintide | Amylin | In clinical trials | 5-10 mg |
| Cagrilintide + Semaglutide | Amylin, GLP-1 | Components studied and registered | 2.5 + 2.5 to 10 + 10 mg |
| Retatrutide + Cagrilintide | GIP, GLP-1, glucagon, amylin | Components in clinical trials | 5 + 5, 10 + 10 mg |
| Tirzepatide + Cagrilintide | GIP, GLP-1, amylin | Tirzepatide registered, cagrilintide in trials | 10 + 10 mg |
Blends in one vial
Blends let researchers study the combined action of several signals in one system. Cagrilintide with semaglutide mirrors the combination studied clinically as CagriSema. Retatrutide with cagrilintide combines GIP, GLP-1, glucagon and amylin receptors, while tirzepatide with cagrilintide pairs GIP, GLP-1 and amylin.
Molecular structure
- Tirzepatide: 39 amino acids with a C20 fatty acid chain, molecular mass 4813.5 g/mol.
- Retatrutide: about 39 amino acids with a lipid chain, molecular mass 4731.3 g/mol.
- Semaglutide: molecular mass 4113.6 g/mol.
- Liraglutide: molecular mass 3751.2 g/mol.
Working in the lab
- Every batch comes with purity confirmed by HPLC.
- Molecular mass is confirmed by mass spectrometry (MS).
- Store the lyophilised powder as described on each product page, away from light.
- Convert concentrations with the concentration calculator.
- All substances are sold as research reagents, see Research Use Only.
Why buy incretin analogues for research from MOLEVIA
- Purity of at least 99%, confirmed by HPLC.
- Same-day dispatch for orders placed by 2 pm on business days.
- InPost parcel locker in Poland on the next business day, DPD courier across Europe in 2-4 business days.
- Shipping to 29 European countries.
- Free delivery from 75 EUR, 65 GBP, 80 USD.
- Quantity discount applied automatically: 5% for 2 items, 10% for 3, 15% for 5.
- Free 10 ml bacteriostatic water with orders from 50 EUR (40 GBP, 55 USD) that contain a peptide vial.
- Pay online by card, Apple Pay, Google Pay or BLIK (PLN only).
Browse the shop and order your incretin analogues today.
Frequently asked questions
What does the Incretin Analogues category include and how is purity checked?
The category offers twelve products, from single GLP-1 agonists such as semaglutide to the triple agonist retatrutide and blends in one vial. Every batch is tested by HPLC, which confirms purity of 99% or higher, and the molecular mass is confirmed by mass spectrometry (MS).
In what form are the peptides supplied and how should I store them?
Incretin analogues are supplied as lyophilised powder in vials. Store the vial sealed and away from light, as described on each product page. Work out concentrations with the concentration calculator before you plan an experiment.
How fast does my order ship and how is it delivered?
Orders placed by 14:00 on a business day ship the same day, and later orders ship the next business day. In Poland, an InPost Paczkomat locker delivers on the next business day for PLN 14.99, free from EUR 75. A DPD courier delivers across 29 European countries in 2-4 business days.
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