Survodutide: research overview
What is survodutide
Survodutide, known in the literature by the designation BI 456906, is a synthetic research peptide from the incretin analogue family. It belongs to a group of compounds studied on two receptors at the same time, which makes it one of the more interesting subjects in metabolic research. Every batch is made in a controlled synthesis process.
Mechanism described in research
Survodutide is a dual agonist of the glucagon and GLP-1 receptors. In in vitro work and animal models, researchers described how activating both receptors affects cell signalling, glucose homeostasis and body weight in the models. The compound has also been studied in clinical trials. This is information from the scientific literature, not a recommendation for any use.
Research areas
- Signalling through glucagon and GLP-1 receptors in cell models
- Glucose homeostasis in preclinical studies
- Body weight and energy balance in animal models
- Lipid metabolism in in vitro work
- Comparisons with other incretin receptor agonists
Reagent specification
| Parameter | Value |
|---|---|
| Name | Survodutide |
| Research designation | BI 456906 |
| Form | lyophilized powder |
| Purity | ≥ 99% (HPLC) |
| Mass confirmation | mass spectrometry (MS) |
| Available sizes | 10 mg |
Working in the laboratory
Store the lyophilized powder at -20 °C in a tightly sealed vial, protected from light. After reconstitution, keep the solution at 2-8 °C. Avoid repeated freezing and thawing, because repeated temperature changes lower the stability of the peptide. Prepare the solution shortly before the planned experiment.
Role of the solvent
- Bacteriostatic water dissolves the lyophilized powder into a working solution. Its preservative keeps microbial growth under control in a multi-use vial.
- Dilute acetic acid is used when the research protocol calls for an acidic environment during dissolution.
Batch quality
Every batch is tested by HPLC, and purity is at least 99%. Mass spectrometry (MS) confirms the molecular mass, so you know the vial contains exactly the compound you ordered.
Ordering and shipping
Orders placed by 14:00 on a business day ship the same day. An InPost Paczkomat in Poland delivers the next business day, and DPD delivers to 29 European countries in 2-4 business days. Shipping is free from 75 EUR, 65 GBP, 80 USD. Orders from 50 EUR (40 GBP, 55 USD) that include a peptide vial come with 10 ml of bacteriostatic water free of charge. Pay online by card, Apple Pay, Google Pay or BLIK (PLN only).
Related products
- Retatrutide is another incretin receptor agonist, often compared with survodutide in the literature.
- Tirzepatide acts on the GIP and GLP-1 receptors and is one of the best documented compounds in this group.
- Semaglutide is a classic GLP-1 agonist and a useful reference point for signalling studies.
Browse the full range in the incretin analogues category. You can also review our quality standards and use the concentration calculator to work out the solution for your chosen solvent volume.
