Semax + Selank: research overview
What is Semax + Selank
Semax + Selank is a ready blend of two synthetic heptapeptides in one vial of lyophilized powder, supplied at 10 mg of each component. Both peptides were developed in Russia. Their short, well-defined chains make identity and batch consistency easy to verify with analytical methods.
Semax is a heptapeptide with the sequence Met-Glu-His-Phe-Pro-Gly-Pro. Its N-terminal part corresponds to a fragment of the ACTH hormone, and the Pro-Gly-Pro end was added during work on the analogue.
Selank is a heptapeptide with the sequence Thr-Lys-Pro-Arg-Pro-Gly-Pro. Its core is based on tuftsin, a natural tetrapeptide, and the Pro-Gly-Pro tail was added in the design of the analogue.
Both peptides have been studied in animal models and in vitro systems. According to the published literature, both were examined in clinical studies in Russia, where they are registered as medicines.
Mechanism described in research
In vitro and animal studies have described the influence of Semax on gene expression in neural tissue and on levels of BDNF, a neurotrophic factor. Selank has been studied for its effect on neurotransmission and on the metabolism of enkephalins, which are endogenous opioid peptides.
Results depend on the model, concentration and exposure time, so treat them as a starting point for your own research design rather than a conclusion. Both components sit in one vial, so your experimental setup starts from one product and one documented batch.
Research areas
- Neurobiology and neurotransmission in cell models
- Gene expression and neurotrophic factors in cultures
- Enkephalin metabolism in biochemical assays
- Stress response in animal research models
- Peptide stability and enzymatic degradation in analytical work
Product specification
| Parameter | Value |
|---|---|
| Name | Semax + Selank, blend in one vial |
| Composition | Semax 10 mg + Selank 10 mg |
| Semax sequence | Met-Glu-His-Phe-Pro-Gly-Pro |
| Selank sequence | Thr-Lys-Pro-Arg-Pro-Gly-Pro |
| Form | lyophilized powder |
| Purity | ≥ 99% (HPLC) |
| Available sizes | 10 mg + 10 mg |
Working in the laboratory
Storage
- Keep the lyophilized powder at -20 °C, tightly sealed and protected from light.
- Once reconstituted, store the solution at 2-8 °C.
- Avoid repeated freezing and thawing. Divide the solution into working aliquots so each one is used once.
Solvent
- Bacteriostatic water is the standard solvent in laboratory practice.
- Water with a small amount of acetic acid is used in some protocols. The acid helps dissolve peptides with a basic character, and selank contains lysine and arginine.
- Orders of 50 EUR (40 GBP, 55 USD) or more that include a peptide receive 10 ml of bacteriostatic water free of charge.
Before first use, record the reconstitution date, batch number and working concentration. This keeps your results reproducible and your documentation complete.
Batch quality
Every batch is tested by HPLC, which confirms purity of at least 99% and shows the presence of impurities. Mass spectrometry (MS) confirms the molecular mass of both components.
Learn more about our quality control on the quality page. Convert your solutions with the concentration calculator. Browse the full range in the neuropeptides category.
