SNAP-8: research overview
What is SNAP-8
SNAP-8, also known as acetyl octapeptide-3, is a synthetic peptide built from eight amino acid residues. Its structure follows a fragment of SNAP-25, a protein from the SNARE family. That makes SNAP-8 one of the skin peptides that appear in cosmetic research and in work on cellular mechanisms.
We supply it as a research use only (RUO) chemical in lyophilized form. Each vial is a ready portion for your work, with no preparation step on the laboratory side.
Mechanism described in research
SNARE proteins form a complex that brings vesicles to the cell membrane and controls the release of neurotransmitters. SNAP-25 is one of its key components.
In vitro studies have described how SNAP-8 can compete with natural SNAP-25 for a place in assembling the SNARE complex. This changes the course of exocytosis in a cell model, which is why SNAP-8 is often chosen as a tool for studying signalling and neurotransmitter release.
Research areas
- in vitro models: SNARE complex assembly and exocytosis
- cell models: signalling and neurotransmitter release
- cosmetic research on peptides that act on the skin
- formulation work and comparisons of skin peptides in the laboratory
Product specification
| Parameter | Value |
|---|---|
| Name | SNAP-8 (acetyl octapeptide-3) |
| CAS number | 868844-74-0 |
| Formula | C41H70N16O16S |
| Molecular mass | 1075.2 g/mol |
| Form | lyophilized powder |
| Purity | 99% or higher (HPLC) |
| Available sizes | 10 mg, 100 mg |
| Category | skin peptides |
Working with SNAP-8 in the lab
Storing the lyophilized powder
Keep the vial at -20 °C, tightly sealed and away from moisture. Keep it in these conditions from delivery until you start your work.
Solution after reconstitution
Once dissolved, keep the solution at 2-8 °C. Avoid repeated freezing and thawing by dividing the solution into working aliquots that you can use within a short period.
The role of water
Water is the solvent in which you prepare your working solution. Bacteriostatic water is a convenient choice for this step. On orders from 50 EUR (40 GBP, 55 USD) that include a peptide vial, we add 10 ml of bacteriostatic water free of charge.
Batch quality
Every batch goes through HPLC analysis, and the purity result in our shop is 99% or higher. We confirm the molecular mass by mass spectrometry (MS).
Related products
For skin research, SNAP-8 pairs well with other peptides from the same category: GHK-Cu, AHK-Cu and Matrixyl.
The full range is listed in the skin peptides category. You can read about quality control on the quality page, and convert your concentration with the concentration calculator.
