HGH Fragment 176-191: research overview
What HGH Fragment 176-191 is
HGH Fragment 176-191 is a synthetic peptide that corresponds to residues 176 to 191 of the growth hormone chain. It is a C-terminal fragment, a segment that sits at the end of the full molecule and has a distinct role within it.
Full growth hormone is a large, multifunctional protein. Working with an isolated fragment lets you narrow the research question to one well-defined part of the molecule. Your results can then be linked to that specific segment rather than to the whole hormone.
Mechanism described in research
Lipolysis models, which study the breakdown of triglycerides stored in adipose tissue cells, have been used to examine how this fragment influences the process under laboratory conditions.
The key observation concerns insulin-like growth factor 1 (IGF-1). In animal models, the fragment did not raise IGF-1 levels, unlike the full growth hormone. That difference makes the fragment a practical tool for separating metabolic effects from the IGF-1 pathway in experimental design.
Research areas
- Lipolysis and lipid metabolism in in vitro models
- Comparison of the fragment with full growth hormone in animal models
- Metabolic pathways that operate independently of IGF-1
- Relationship between fragment structure and activity in structural studies
Product specifications
| Parameter | Value |
|---|---|
| Name | HGH Fragment 176-191 |
| Category | Metabolic research |
| Form | lyophilized powder |
| Purity | 99% or higher (HPLC) |
| Molecular mass | confirmed by MS |
| Available sizes | 1 mg, 2 mg, 5 mg, 10 mg, 15 mg |
Working in the laboratory
Storage and reconstitution
| Form | Temperature | Rules |
|---|---|---|
| Lyophilized powder | -20 °C | tightly closed, protected from light and moisture |
| Solution after reconstitution | 2-8 °C | divide into aliquots, avoid repeated freezing and thawing |
Choose the solvent to match your experiment. Bacteriostatic water is a convenient solvent in laboratory work, and bacteriostatic water in our shop is ready for lab use. Water with acetic acid is an alternative that some researchers use with selected peptides, following their own laboratory protocol. See acetic acid water.
Batch quality
Each batch is tested by HPLC, which confirms purity of at least 99%. Mass spectrometry (MS) confirms the molecular mass. The batch number brings both results together, so you always know which material enters your laboratory. Read more on the quality page.
Shipping and ordering
| Item | Terms |
|---|---|
| Same-day dispatch | orders placed by 14:00 on a business day |
| InPost parcel locker | Poland, next business day |
| DPD | Europe, 2-4 business days |
| Free shipping | from 75 EUR, 65 GBP or 80 USD |
| Volume discount | 2 pcs -5%, 3 pcs -10%, 5 pcs -15%, applied automatically |
| Free gift | 10 ml bacteriostatic water with orders from 50 EUR (40 GBP, 55 USD) that include a peptide vial |
| Payments | Card, Apple Pay, Google Pay, BLIK (PLN only) |
Related products
- AOD-9604, a fragment of the same growth hormone segment with an added tyrosine
- MOTS-c, a mitochondria-derived peptide studied in metabolic research
- SLU-PP-332, a compound studied in metabolic models
Browse the full range in the metabolic research category. To calculate the volume for your target concentration, use the concentration calculator.
