GHRP-6: research overview
What is GHRP-6
GHRP-6 is a synthetic hexapeptide, a compound built from six amino acid residues linked by peptide bonds. It belongs to the growth hormone secretagogue family (GHRPs) and is one of the first described members of that group. It is produced by chemical synthesis, which lets you check and document the composition of every batch.
Knowing the structure makes your work easier to plan. The molecular mass is 873 g/mol and the molecular formula is C46H56N12O6. These two figures let you convert the weight of the lyophilized powder into the concentration of your solution, the starting point of any experimental design.
Mechanism described in research
GHRP-6 acts as an agonist of the ghrelin receptor GHS-R1a, which is found among other places in the pituitary gland and the hypothalamus. In vitro studies have observed pituitary cells releasing growth hormone (GH) under stimulation. Animal model studies have also described effects on appetite signalling, which makes GHRP-6 a useful comparator in research on ghrelin biology.
Results from one experimental system do not automatically carry over to another. A sound study design includes proper controls, verified concentrations and clearly defined conditions.
Research areas
- Neuroendocrinology and regulation of growth hormone secretion
- Ghrelin signalling and the GHS-R1a receptor
- The GH/IGF-1 axis in in vitro and animal models
- Regulation of food intake in animal research
- Comparative studies of growth hormone secretagogues
Product specification
| Parameter | Value |
|---|---|
| Name | GHRP-6 |
| CAS number | 87616-84-0 |
| Molecular formula | C46H56N12O6 |
| Molecular mass | 873 g/mol |
| Form | Lyophilized powder |
| Purity | 99% or higher (HPLC) |
| Available sizes | 5 mg, 10 mg |
| Intended use | Research use only (RUO) |
Working in the laboratory
Storage
Keep the lyophilized powder at -20 °C, tightly sealed and protected from moisture. Once reconstituted, store the solution at 2-8 °C. Avoid repeated freezing and thawing, because each cycle stresses the material.
Dissolving and reconstitution
Water is the most common solvent. Bacteriostatic water is also widely used in laboratory work, since it limits bacterial growth when a vial is sampled many times. If water does not dissolve the lyophilized powder well enough, protocols sometimes use dilute acetic acid as a secondary solvent. Your protocol sets the volume and concentration, and the concentration calculator converts the weight into a solution concentration.
Batch quality
At MOLEVIA, every batch goes through HPLC analysis, which confirms purity of 99% or higher. Mass spectrometry (MS) confirms the molecular mass of 873 g/mol. Each batch is identified by its batch number, so you can match the HPLC and MS results to a specific vial. Details are on our quality page.
Ordering and shipping
Orders placed by 14:00 on a business day ship the same day. Delivery is free from 75 EUR, 65 GBP or 80 USD. Quantity discounts apply automatically: 5% for 2 items, 10% for 3 and 15% for 5. Orders from 50 EUR (40 GBP, 55 USD) that include a peptide vial get 10 ml of bacteriostatic water free. Pay online by card, Apple Pay, Google Pay or BLIK (PLN only).
Related products
- Ipamorelin: a pentapeptide from the same growth hormone secretagogue family, with a different structure
- GHRP-2: a closely related hexapeptide from the GHRP family
- CJC-1295 no DAC: a GHRH analogue that complements research on the growth hormone axis
Browse the full range in the GH axis category.
